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Connolly Hospital Dublin
Our Lady of Lourdes Hospital Library, Drogheda (1)
Roscommon University Hospital (1)
St. Luke’s Radiation Oncology Network Dublin (4)
University Hospital Waterford (1)
Author
Aherne, Noel
(2)
Aherne, Noel J
(1)
Armstrong, John, G
(1)
Gillham, C.M
(1)
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AIMS: To report cancer-specific and health-related quality-of-life outcomes in patients undergoing radical chemoradiation (CRT) alone for oesophageal cancer. MATERIALS AND METHODS: Between 1998 and 2005, 56 patients with oesophageal cancer received definitive radical CRT, due to local disease extent, poor general health, or patient choice. Data from European Organization for Research and Treatment of Cancer quality-of-life questionnaires QLQ-30 and QLQ-OES24 were collected prospectively. Questionnaires were completed at diagnosis, and at 3, 6 and 12 months after CRT where applicable. RESULTS: The median follow-up was 18 months. The median overall survival was 14 months, with a 51, 26 and 13 1-, 3- and 5-year survival, respectively. At 12 months after treatment there was a significant improvement compared with before treatment with respect to dysphagia and pain. Global health scores were not significantly affected. CONCLUSIONS: Considering the relatively short long-term survival for this cohort of patients, maximising the quality of those final months should be very carefully borne in mind from the outset. The health-related quality-of-life data reported herein helps to establish benchmarks for larger evaluation within randomised clinical trials (1)
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We report the case of a 41-year-old mentally retarded male with recurrent pilomatrix carcinoma of the occipital region which invaded the occipital bone, left cerebellum and left temporal lobe. At his initial presentation the patient had a craniotomy and subtotal excision of the lesion with positive margins. He received no adjuvant therapy. After an early intracranial recurrence he had subtotal debulking and was referred for external beam radiotherapy. At 27 months follow-up after adjuvant external beam radiotherapy the intracranial component has not progressed and the patient remains clinically well (1)
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1)
Recurrent malignant pilomatrixoma invading the cranial cavity: Improved local control with adjuvant radiation
Author
Aherne, Noel
Publisher
Staff Publications
Pub. Date
2009
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2)
Abnormal hCG levels in a patient with treated stage 1 seminoma: a diagnostic dilemma
Author
Aherne, Noel
Publisher
Staff Publications
Pub. Date
2008
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3)
100 clinical cases and osces in surgery
Author
Aherne, Noel J
Publisher
Pastest
Pub. Date
2004
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4)
Quality of life and survival in patients treated with radical chemoradiation alone for oesophageal cancer
Author
Gillham, C.M
Publisher
Staff Publications- Hollywood, Donal
Pub. Date
2008
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5)
Pilomatrix carcinoma presenting as an extra axial mass: clinicopathological features
Author
Armstrong, John, G
Publisher
Staff Publications- Aherne, Noel J
Pub. Date
2008
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