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Connolly Hospital Dublin
St. Luke’s Radiation Oncology Network Dublin (179)
Author
Armstrong, John, G
(19)
Carney, Desmond
(8)
Herity, Bernadette A
(8)
Murphy, Anne
(8)
Faul, Clare
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A case-control study of 100 cases of malignant melanoma (MM) and 100 matched controls has been completed. The male:female ratio of patients with MM was 1:2.4, which is similar to that found in other European studies and the mean age was 49.1 years (range 19-82 years). Significant differences were seen between cases and controls for area of residence and social class, more cases than controls came from rural areas (P = 0.007) and cases were of higher social class than controls (P = 0.003) and had attained a higher level of education (P = 0.005). Phenotypic differences between cases and controls were also observed, namely cases were more likely to have light coloured (blue/grey/green) eyes (P = 0.003) and to have had fair/red hair at age 20 (P = 0.004). Cases were also more likely than controls to dislike exposure to hot sun (P = 0.008) to report sunburning easily (P = 0.001) and to have experienced episodes of sunburn with blistering more frequently than controls (P = 0.01). History of longterm exposure to ultraviolet radiation (UV) through working outdoors, leisure activities, living abroad in sunny climates, or sun holidays was similar between cases and controls. This study supports evidence from elsewhere that episodes of acute sunburn in susceptible individuals increase risk of MM and that longterm regular exposure to UV which is important in non-melanoma skin cancer does not play a major role in the development of MM (1)
A seventy two year old man presented to the Emergency Department with clinical features of colonic obstruction. Subsequent radiological investigations confirmed this impression and revealed the aetiology to be compression of the sigmoid colon against the sacrum by a massively distended urinary bladder. Chronic urinary retention due to benign prostatic hypertrophy is an extremely unusual cause of large bowel obstruction. Little in this patient�s clinical findings suggested this aetiology. We reviewed the literature in this area and highlight the benefits of CT scanning over contrast studies (1)
AIM: The feasibility and improved efficacy of six conventional fractions per week has previously been proven in a Danish randomized trial. We tested the tolerance and efficacy of seven conventional fractions per week using a concomitant boost technique. METHODS: From September 1996 to May 1998, 20 patients with squamous cancer of the head and neck were treated with radiation alone. The site of disease was oropharynx in 35, larynx in 30, oral cavity 20, and hypopharynx in 15. All patients had stage III (10)/IV (90) disease. The planned total dose to gross disease was 66 Gy delivered in 33 fractions of 2 Gy each in 31 days. Large volumes were treated to 46 Gy, 2 Gy per fraction, once each morning, Monday-Friday. Boosts to gross disease consisted of 20 Gy in 10 fractions (1)
AIMS: To report cancer-specific and health-related quality-of-life outcomes in patients undergoing radical chemoradiation (CRT) alone for oesophageal cancer. MATERIALS AND METHODS: Between 1998 and 2005, 56 patients with oesophageal cancer received definitive radical CRT, due to local disease extent, poor general health, or patient choice. Data from European Organization for Research and Treatment of Cancer quality-of-life questionnaires QLQ-30 and QLQ-OES24 were collected prospectively. Questionnaires were completed at diagnosis, and at 3, 6 and 12 months after CRT where applicable. RESULTS: The median follow-up was 18 months. The median overall survival was 14 months, with a 51, 26 and 13 1-, 3- and 5-year survival, respectively. At 12 months after treatment there was a significant improvement compared with before treatment with respect to dysphagia and pain. Global health scores were not significantly affected. CONCLUSIONS: Considering the relatively short long-term survival for this cohort of patients, maximising the quality of those final months should be very carefully borne in mind from the outset. The health-related quality-of-life data reported herein helps to establish benchmarks for larger evaluation within randomised clinical trials (1)
Adjuvant radiotherapy in Stage I endometrial cancer. Where do we stand? (1)
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ST. LUKE'S PUBLICATION ARCHIVE
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1)
Merkel Cell Carcinoma Metastasis to the Iris in a 23 Year Old Female
Author
Carney, Desmond
Pub. Date
2009
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2)
Nurse prescribing in Ireland
Author
Leonard, Kay
Pub. Date
2009
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3)
Radiation therapy hits home
Author
Faul, Clare
Pub. Date
2007
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4)
The prevention and early detection of cancer
Author
Herity, Bernadette A
Pub. Date
1983
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5)
The current status of adjuvant hormonal therapy combined with radiation therapy for localised prostate cancer
Author
Armstrong, John, G
Pub. Date
1998
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6)
Carboplatin/etoposide combination chemotherapy in the treatment of poor prognosis patients with small cell lung cancer
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Carney, Desmond
Pub. Date
1995
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7)
A phase II trial for the optimisation of treatment position in the radiation therapy of prostate cancer
Author
Armstrong, John, G
Publisher
Staff Publications- Mairin Cannon
Pub. Date
2008
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8)
Oncology: Abstracts prepared by Dr. Brian O'Neill
Author
O'Neill, Brian
Pub. Date
2003
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9)
Prophylactic cranial irradiation and small-cell lung cancer
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Carney, Desmond
Pub. Date
1999
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10)
Adjuvant radiation therapy for early breast cancer
Author
Faul, Clare
Pub. Date
2003
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11)
Evolving trends and essentials in the diagnosis and management of anal cancer
Author
Walsh, Lorraine
Pub. Date
2009
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12)
Watching for reaction
Author
Murphy, Anne
Pub. Date
2003
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13)
Head and neck cancers: A team approach
Author
Murphy, Anne
Pub. Date
2006
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14)
The management of prostate cancer
Author
Armstrong, John, G
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15)
The diagnosis and management of prostate cancer
Author
Armstrong, John, G
Pub. Date
1998
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16)
Oral hygiene a priority of care
Author
Murphy, Anne
Pub. Date
2002
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17)
Acute Colonic Obstruction Due to Benign Prostatic Hypertrophy
Author
McDermott, E
Pub. Date
2009
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18)
Wound care: making it better
Author
Murphy, Anne
Pub. Date
2008
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19)
Exploring Holism
Author
Laffan, Grace
Pub. Date
December 1995
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20)
Alpha-interferon does not increase the efficacy of 5-fluorouracil in advanced colorectal cancer
Author
Thirion, Pierre
Pub. Date
2001
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